The Manitoba Follow-up Study, now in its 69th year, is Canada's largest and longest running investigation of cardiovascular disease. Housed at the University of Manitoba since its inception on July 1, 1948, MFUS has followed a cohort of 3,983 healthy young men with annual contact and routine medical examinations amassing a database with which to study the natural history of cardiovascular disease.

MFUS is ongoing - on January 1, 2017, from among the original cohort of 3,983 men, 3,791 had a confirmed date of death. Of the 192 men considered alive, we've heard from over 70% in the past year.

While analysis of electrocardiographic abnormalities, blood pressure patterns and heart disease continue, parallel analyses are also investigating issues concerning relationships between successful aging, functioning, and health.